1200 "No Benefit from Amoxicillan"
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Dynamic Chiropractic – March 10, 1997, Vol. 15, Issue 06

"No Benefit from Amoxicillan"

By Editorial Staff
A randomized double blind clinical trial of children ages 3-6 recently released from the Agency for Health Care Policy and Research (AHCPR), concluded that "there was no benefit from amoxicillan prophylaxis compared to a placebo control in preventing new AOM (acute otitis media) episodes."

Free of AOM (%)

30-90 Days:

Placebo Group:71% Otitis Free
Daily Amoxicillan Group: 65% Otitis Free
Twice Daily Amoxicillan Group: 62% Otitis Free

3 Months or Longer:

Placebo Group:54% Otitis Free
Daily Amoxicillan Group: 63% Otitis Free
Twice Daily Amoxicillan Group: 60% Otitis Free


SOURCE: Berman S.

Continuous twice daily or once daily amoxicillan prophylaxis compared to placebo for children with recurrent otitis media. Agency for Health Care Policy and Research grant no.: RO3 HS07283-02.


Dynamic Chiropractic editorial staff members research, investigate and write articles for the publication on an ongoing basis. To contact the Editorial Department or submit an article of your own for consideration, email .


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