The British Journal of Hospital Medicine1 recently published, "Failure of many new heart-failure drugs: the need for vasoconstrictor rather than vasodilator agents?" The author examines the theories behind the use of these drugs and questions the use of various drugs for heart failure.
"There is obvious reluctance to throw away the haemodynamic 'compass' because although this may have led us in the wrong direction, at least when we believed in it, we thought we knew where we were going!"Reference
1. Cleland JGF. Failure of many new heart-failure drugs: the need for vasoconstrictor rather than vasodilator agents? Br J Hosp Med 1994;52:193-6.
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